Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage
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چکیده
منابع مشابه
Rodent models of intracerebral hemorrhage.
The collagenase and whole blood intracerebral hemorrhage (ICH) models are widely used to identify mechanisms of injury and to evaluate treatments. Despite preclinical successes, to date, no treatment tested in phase III clinical trials has benefited ICH patients. These failures call into question the predictive value of current ICH models. By highlighting differences between these common rodent...
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Introduction: cerebral vein thrombosis is a rare complication of nephrotic syndrome (NS).We report a known case of NS with hemorrhagic thrombosis. Case report: A boy with previous history of NS was admitted with headache and decrease of level of consciousness and his brain images were revealed hemorrhagic thrombosis Conclusions: cerebral vein thrombosis must be considered in patients with...
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BACKGROUND Cerebral vasospasm is commonly seen in subarachnoid hemorrhage. However the vasospasm in spontaneous intracerebral hemorrhage without subarachnoid extension has not been described. REPORT We report a patient who developed intracerebral hemorrhage associated with cerebral vasospasm demonstrated by conventional angiography. The vasospasm involved the superior and inferior divisions o...
متن کاملDynamic cerebral autoregulation in acute intracerebral hemorrhage.
BACKGROUND AND PURPOSE Cerebral autoregulation (CA) is not universally impaired in acute intracerebral hemorrhage (ICH); however, the dynamic components of CA are probably more vulnerable. This study, therefore, evaluates the time course of dynamic CA in acute ICH and its relationship to clinical outcome. METHODS Twenty-six patients with ICH were studied on days 1, 3, and 5 after ictus. Dynam...
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Background: Intracerebral hemorrhage (ICH) is a type of intracranial bleed that occurs within the brain tissue or ventricles. The present study aimed to review the association between ICH and cerebral palsy (CP) in the preterm infants. Materials and Methods: <s...
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ژورنال
عنوان ژورنال: Experimental Neurology
سال: 2013
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2012.12.009